Blog Archives

The Elusive Nature of APOE ε4 in Mid-adulthood: Understanding the Cognitive Profile

Objectives: The apolipoprotein E (APOE) ε4 allele is an established risk factor for dementia, yet this genetic variant is associated with a mixed cognitive profile across the lifespan. This study undertakes both a systematic and meta-analytic review of research investigating APOE-related differences

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Posted in Publications, Research

Dementia in the clinic

One of my PhD colleagues, Rebecca Atkinson, wrote recently that each student at Sussex funded by the Alzheimer’s Society charity is afforded the opportunity to complete placements in a local Memory Assessment Services (MAS) clinic. I was paired with Consultant

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Posted in Lab Life

The APOE paradox: do attentional control differences in mid-adulthood reflect risk of late-life cognitive decline

Possession of an APOE e4 allele is an established risk factor for Alzheimer’s disease, while the less commonly studied e2 variant is premised to offer some protection. This research explores the purported deleterious-protective dichotomy of APOE variants on attentional control in mid-adulthood. 66 volunteers,

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Posted in Publications, Research

A clinical perspective: visiting the Memory Assessment Services

As a PhD student, the funding for my studentship comes from the Alzheimer’s Society. This is part of an Alzheimer’s Society Doctoral Training Centre at the University of Sussex, which supports the research of eight PhD students from multiple disciplines

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Posted in Lab Life, Uncategorized

Advances in Hepatitis C research: associated neurocognitive symptoms

Hepatitis C virus (HCV) is a major health burden in England (Public Health England, 2015). HCV treatment is a significant component in control of the disease but the neuropsychiatric side effects of the treatment have been associated with treatment interruption.

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Posted in Research, Uncategorized

Alzheimer’s Research UK 2016 Conference – II

Day 1 The themes of the 1st day of the main AD conference were Frontotemporal dementia, Neurovascular dysfunction, and Inflammation & Immunity. One of many fascinating presentations on this was given by Jessica Duncombe, a 3rd year PhD student from

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Posted in Events, News, Research, Uncategorized

Alzheimer’s Research UK 2016 Conference

  This week I attended the annual ARUK conference, in Manchester. This comprised a PhD day, followed by two days of the main conference. The PhD day included a number of talks from current PhD students on their research, as

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Posted in Events

Bake-Off Win at the Life Science Impact Day

Professor Louise Serpell, co-Director of the Alzheimers Society DTC and the Dementia Reseearch Group won second prize at the Life Sciences Impact Day Bake-off with this wonderful Neuron Cake! Her kids ate most of the mitochondria…

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Posted in Lab Life

Rachel Clarke on Beginning my PhD…

I have been lucky enough to secure a studentship which started at The University of Sussex in September. It is linked to my previous role on the IDEAL study – Improving the Experience of Dementia and Enhancing Active Life: living well with dementia (http://www.idealproject.org.uk/).

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Posted in Lab Life